NHEJ End resection

RIF1

Replication timing regulatory factor 1

Short entry. It states only what the cited sources say; it will grow as more sources are read.

Anti-resection (NHEJ commitment)

Replication timing regulatory factor 1

Described as acting with 53BP1 as an antagonist of end resection. [1][2]

Interactions
53BP1

References

  1. Chang et al. · 2017Non-homologous DNA end joining and alternative pathways to double-strand break repair
  2. Escribano-Díaz et al. · 2013A cell cycle-dependent regulatory circuit composed of 53BP1-RIF1 and BRCA1-CtIP controls DNA repair pathway choice
Read the HRD article