Homologous recombination Resolution

Synthesis

Repair DNA synthesis

Short entry. It states only what the cited sources say; it will grow as more sources are read.

Process or outcome

Repair DNA synthesis

The invading 3′ end primes DNA synthesis. With purified human proteins, DNA polymerase δ extended RAD51-made recombination intermediates, dependent on PCNA. [1]

Interactions
Pol δ, PCNA
In the pathway

References

  1. Sneeden et al. · 2013Reconstitution of recombination-associated DNA synthesis with human proteins
  2. Paliwal et al. · 2014Human RECQ5 helicase promotes repair of DNA double-strand breaks by synthesis-dependent strand annealing
Read the HRD article