Homologous recombination End resection
EXO1
Exonuclease 1
Short entry. It states only what the cited sources say; it will grow as more sources are read.
End resection
Exonuclease 1
Nuclease that extends the 3′ single-stranded tails created by MRN and CtIP. In vitro it has 5′→3′ exonuclease activity on double-stranded DNA and 5′-flap endonuclease activity. [1][2]
- Interactions
- MRN, CtIP
- In the pathway
- CtIP leads to it Chang et al. · 2017
- leads to RPA Chang et al. · 2017
References
- Chang et al. · 2017Non-homologous DNA end joining and alternative pathways to double-strand break repair
- Symington & Gautier · 2011Double-strand break end resection and repair pathway choice